Comparative analysis of antimicrobial potential of selected plant extracts against E. coli, Salmonella, and Malassezia

Umber Gul; Rabia Shaheen; Zahida Nasreen; Aneela Sharif; Amjid Khan; Khurram Shahzad Munawar

doi:10.53992/njns.v9i2.176

Authors

Umber Gul Department of Zoology, University of Mianwali, 42200, Punjab, Pakistan
Rabia Shaheen Department of Botany, University of Sargodha, 40100, Punjab, Pakistan
Zahida Nasreen Department of Zoology, University of Mianwali, 42200, Punjab, Pakistan
Aneela Sharif Department of Zoology, University of Mianwali, 42200, Punjab, Pakistan
Amjid Khan Molecular Systematics and Applied Ethnobotany Lab (MOSAEL), Department of Plant Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan
Khurram Shahzad Munawar Institute of Chemistry, University of Sargodha, 40100, Punjab, Pakistan

DOI:

https://doi.org/10.53992/njns.v9i2.176

Keywords:

Antimicrobial activities, Human pathogens, Medicinal plants, Well diffusion method

Abstract

The present study is conducted to analyze the antifungal and antibacterial potential of some plants against three species of human pathogenic microbes i.e. E. coli, Salmonella, and Malassezia. The antimicrobial activity of ethanolic and methanolic extracts of Calotropis procera, Prosopis juliflora, and Ziziphus nummularia was assessed by employing a good diffusion method in agar. Overall results demonstrated the highly significant activity of Ziziphus nummularia against E. coli, Ziziphus nummularia, and Calotropis procera against Salmonella and Calotropis procera against Malassezia. Of three dilutions used, 1.0 ml, 0.8 ml, and 0.6 ml, the 1 ml dilution of methanolic extract of Ziziphus nummularia and Calotropis procera exhibited potential effectiveness against E. coli and Salmonella. While 1.0 ml dilution of ethanolic extract of Calotropis procera showed the best antibacterial activity. However, Prosopis juliflora leaf extract was found to be less effective against selected pathogens.